Abstract Title:

The effect of microwave irradiation on DNA hybridization.

Abstract Source:

Org Biomol Chem. 2009 Jun 21 ;7(12):2506-8. Epub 2009 May 1. PMID: 19503920

Abstract Author(s):

Wesleigh F Edwards, Douglas D Young, Alexander Deiters

Article Affiliation:

Wesleigh F Edwards


The effect of microwave irradiation on DNA/DNA hybridization has been studied under controlled power and temperature conditions. It was discovered that microwave irradiation led to the melting of double-stranded deoxyoligonucleotides well below their thermal melting temperature and independent of the length of the deoxyoligonucleotides. These observations indicate a specific interaction of microwaves with DNA, and have important implications in the chemical or enzymatic processing of DNA under microwave heating.

Study Type : In Vitro Study

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