The effect of microwave irradiation on DNA hybridization.
Org Biomol Chem. 2009 Jun 21 ;7(12):2506-8. Epub 2009 May 1. PMID: 19503920
Wesleigh F Edwards
The effect of microwave irradiation on DNA/DNA hybridization has been studied under controlled power and temperature conditions. It was discovered that microwave irradiation led to the melting of double-stranded deoxyoligonucleotides well below their thermal melting temperature and independent of the length of the deoxyoligonucleotides. These observations indicate a specific interaction of microwaves with DNA, and have important implications in the chemical or enzymatic processing of DNA under microwave heating.