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Article Publish Status: FREE
Abstract Title:

Molecular Basis of the Therapeutical Potential of Clove (L.) and Clues to Its Anti-COVID-19 Utility.

Abstract Source:

Molecules. 2021 Mar 26 ;26(7). Epub 2021 Mar 26. PMID: 33810416

Abstract Author(s):

Caterina Vicidomini, Valentina Roviello, Giovanni N Roviello

Article Affiliation:

Caterina Vicidomini

Abstract:

The current COronaVIrus Disease 19 (COVID-19) pandemic caused by SARS-CoV-2 infection is enormously affecting the worldwide health and economy. In the wait for an effective global immunization, the development of a specific therapeutic protocol to treat COVID-19 patients is clearly necessary as a short-term solution of the problem. Drug repurposing and herbal medicine represent two of the most explored strategies for an anti-COVID-19 drug discovery. Clove (L.) is a well-known culinary spice that has been used for centuries in folk medicine in many disorders. Interestingly, traditional medicines have used clove since ancient times to treat respiratory ailments, whilst clove ingredients show antiviral and anti-inflammatory properties. Other interesting features are the clove antithrombotic, immunostimulatory, and antibacterial effects. Thus, in this review, we discuss the potential role of clove in the frame of anti-COVID-19 therapy, focusing on the antiviral, anti-inflammatory, and antithrombotic effects of clove and its molecular constituents described in the scientific literature.

Study Type : In Vitro Study

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