Supplementation with Evelle improves skin smoothness and elasticity in a double-blind, placebo-controlled study with 62 women.
J Dermatolog Treat. 2004 Jul;15(4):222-6. PMID: 15764035
OBJECTIVE: To investigate whether nutritional intervention with a proprietary formulation and other micronutrients may favourably alter skin roughness and elasticity. METHODS: Sixty-two women aged 45-73 years participated in a double-blind, placebo-controlled trial testing the efficacy of a proprietary oral supplement for skin nutrition (Evelle), for improvement of skin elasticity and roughness. The active ingredients were vitamins C and E, carotenoids, selenium, zinc, amino acids and glycosaminoglycans, blueberry extract and Pycnogenol. RESULTS: Skin elasticity, measured using an optical cutometer, was found to be statistically significantly increased by 9% after 6 weeks of treatment compared with placebo (p=0.0351). Skin roughness, as evaluated by three-dimensional microtopography imaging, was found to be statistically significantly lowered by 6% compared with the control group after 12 weeks treatment (p=0.0157). CONCLUSION: Evelle can potentially improve visible signs of cutaneous ageing.