Article Publish Status: FREE
Abstract Title:

Anti-inflammatory Effects of the Natural Compounds Cortex Phellodendri and Humulus japonicus on Pelvic Inflammatory Disease in Mice.

Abstract Source:

Int J Med Sci. 2017 ;14(8):729-734. Epub 2017 Jul 18. PMID: 28824307

Abstract Author(s):

Yeonsu Oh, Yong-Soo Kwon, Bae Dong Jung

Article Affiliation:

Yeonsu Oh


Pelvic inflammatory disease (PID) is an inflammatory and/or infectious disorder of the upper female genital tract, including the uterus, fallopian tubes, and adjacent pelvic structures, that may spread upward to the peritoneum. Currently available treatment options have presented to produce adverse effects of various degrees, such as increased antimicrobial resistance and a limited effective duration of hormones. In the study, the Cortex Phellodendri (CP) and Humulus japonicus (HJ) among natural compounds that are believed to present biological activities with fewer side effects were tested in a PID animal model. The results suggested that the administration CP and HJ reduced clinical signs, inflammatory cytokine expression as well as secretion in uterine tissue, and neutrophil infiltration into the tissue.

Study Type : Animal Study

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