New Iridoid Derivatives from the Fruits ofand Their Neuroprotective Activities.
Molecules. 2019 Feb 11 ;24(3). Epub 2019 Feb 11. PMID: 30754635
Three previously undescribed iridoids, cornusfurals A⁻C, were isolated from the ethanolic extracts of fruits of. Their structures were elucidated by spectroscopic methods, including one-dimensional and two-dimensional nuclear magnetic resonance, ultraviolet spectroscopy, infrared spectroscopy, and mass spectrometry. The neuroprotective activity was evaluated by measuring corticosterone-induced damage in PC12 cells. The results showed that cornusfural B decreased corticosterone-induced PC12 cell damage compared with that in model cells.