Abstract Title:

Nigella sativa fixed oil as alternative treatment in management of pain in arthritis rheumatoid.

Abstract Source:

Phytomedicine. 2018 Jul 15 ;46:69-77. Epub 2018 Apr 10. PMID: 30097124

Abstract Author(s):

Mohaddese Mahboubi, Leila Mohammad Taghizadeh Kashani, Mona Mahboubi

Article Affiliation:

Mohaddese Mahboubi


BACKGROUND: N. sativa seeds is the source of fixed oil, which contain fatty acids and thymoquinone. N. sativa fixed oil topically or orally is used traditionally for management of pain in back, joints, musculoskeletal organs and arthritis rheumatoid.

PURPOSE: The aim of this review article was to evaluate the potential effects of N. sativa fixed oil in pain and inflammation, especially in arthritis rheumatoid.

METHODS: All information was extracted from accessible and inaccessible sources (books, electronic sources, thesis and etc.).

RESULTS: The results of our investigation showed N. sativa fixed oil, especially thymoquinone content had valuable anti-inflammatory and analgesic effects via different pathways. The efficacy of thymoquinone as potential treatment was confirmed in different animal model of arthritis and the clinical studies confirmed the oral (n = 4) and topical use (n = 1) of N. sativa fixed oil without adverse effects in patients suffering from arthritis rheumatoid.

CONCLUSION: The larger multicenter clinical trials for comparing the efficacy of topical, oral administrations and current treatment may help to understand better the efficacy of valuable fixed oil.

Study Type : Review

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.