Abstract Title:

[Effects of eight environmental endocrine disruptors on insulin resistance in patients with polycystic ovary syndrome: a preliminary investigation].

Abstract Source:

Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1753-6. PMID: 22027783

Abstract Author(s):

Ting-Ting Li, Liang-Zhi Xu, Yong-Heng Chen, Hong-Mei Deng, Chun-Ying Liang, Ying Liu, Xiao-Fang Liu, Jing Zhang, De-Ying Kang, Dong-Sheng Qiu, Dai-Wen Han, Rong Hu

Article Affiliation:

Department of Obstetrics and Gynecology, West China Second University Hospital, West China Hospital, Sichuan University, Chengdu 610041, China. E-mail: aki-yo@163.com.

Abstract:

OBJECTIVE: To investigate the relationship between 8 endocrine-disrupting chemicals in the serum and insulin resistance in patients with polycystic ovary syndrome (PCOS).

METHODS: This study was conducted among 60 patients with PCOS, including 23 with insulin resistance (PCOS-IR) and 37 without insulin resistance (PCOS-NIR), and 29 non-PCOS women seeking medical attention for infertility or menstrual disorder (control group). The serum levels of 6 phthalic acid esters (PEAs), bisphenol A (BPA) and octylphenol (OP) were measured in all the subjects.

RESULTS: The levels of PAEs, BPA and OP showed no significant differences between PCOS patients and the control group (P>0.05). The serum level of OP was significantly lower in patients PCOS-IR than in those with PCOS-NIR (47.89 ng/ml vs 60.24 ng/ml, P<0.05).

CONCLUSION: PEAs and BPA do not produce obvious effect on the pathogenesis of PCOS or contribute to insulin resistance, but OP may play a role in insulin resistance in PCOS patients.

Study Type : Human Study
Additional Links
Problem Substances : Octylphenol : CK(10) : AC(1)

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.