Abstract Title:

Oral vitamin B12 can change our practice.

Abstract Source:

Postgrad Med J. 2003 Apr;79(930):218-20. PMID: 12743340

Abstract Author(s):

E Nyholm, P Turpin, D Swain, B Cunningham, S Daly, P Nightingale, C Fegan

Article Affiliation:

Yardley Green Medical Centre, Birmingham, UK. Liz.nyholm@pc.birminghamha.wmids.nhs.uk


Oral vitamin B12 can provide an effective alternative to intramuscular injections, so giving patients a choice and reducing costs in primary care. This study investigated the effectiveness, safety, and acceptability of oral vitamin B12 as replacement therapy in patients with vitamin B12 deficiency in a city general practice population. Forty patients previously maintained on vitamin B12 injections were given 1000 micro g of oral cyanocobalamin daily for up to 18 months. All the patients maintained satisfactory serum B12 levels and showed normal haematology and neurology. Compliance and acceptability was excellent. The time for a change in practice has indeed arrived.

Study Type : Commentary

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