Article Publish Status: FREE
Abstract Title:

Analgesic and anti-inflammatory activities of Passiflora foetida L.

Abstract Source:

Asian Pac J Trop Med. 2011 Aug ;4(8):600-3. PMID: 21914535

Abstract Author(s):

V Sasikala, S Saravanan, T Parimelazhagan

Article Affiliation:

V Sasikala


OBJECTIVE: To investigate the analgesic and anti-inflammatory activities of ethanol extract of Passiflora foetida (P. foetida) leaves.

METHODS: Ethanol extract of P. foetida leaf was evaluated for analgesic action by acetic acid-induced writhing and hot plate method in albino mice. The anti-inflammatory property of ethanolic leaf extract was tested by carrageenan induced acute paw edema and histamine induced acute paw edema in rats.

RESULTS: The dose 200 mg/kg of P. foetida leaf extract exhibited highest significant analgesic activity [(13.50±0.43) min] at a reaction time of 20 min in hot plate method in mice. The ethanol extract of leaf dose 100 mg/kg produced a highly significant anti inflammatory effect [(1.302±0.079) mL] in rats.

CONCLUSIONS: It is very clear that P. foetida also has analgesic and anti-inflammatory activities for the pharmaceuticals.

Study Type : Animal Study

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Sayer Ji
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