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Abstract Title:

in Neuropsychiatric Disorders-A Systematic Review.

Abstract Source:

Nutrients. 2020 Dec 19 ;12(12). Epub 2020 Dec 19. PMID: 33352740

Abstract Author(s):

Katarzyna Janda, Karolina Wojtkowska, Karolina Jakubczyk, Justyna Antoniewicz, Karolina Skonieczna-Żydecka

Article Affiliation:

Katarzyna Janda


BACKGROUND: Stress is a natural response of the body, induced by factors of a physical (hunger, thirst, and infection) and/or psychological (perceived threat, anxiety, or concern) nature. Chronic, long-term stress may cause problems with sleep, concentration, and memory, as well as affective disorders. The passionflower () is a perennial plant with documented therapeutic properties. The literature data suggest that the passionflower itself, as well as its preparations, helps reduce stress and can therefore be helpful in the treatment of insomnia, anxiety, and depression. The objective of this systematic review was to evaluatein terms of its neuropsychiatric effects.

METHODS: The scientific databases PubMed, ClinTrials.gov, and Embase were searched up to 22 October 2019. The search identified randomized clinical trials describing the effects ofin neuropsychiatric disorders.

RESULTS: The systematic review included nine clinical trials. The duration of the studies included in the analysis varied widely, from one day up to 30 days. Study participants were no less than 18 years old. In each of the papers, the effects of passionflower were measured by using a number of different tests and scales. The majority of studies reported reduced anxiety levels following the administration ofpreparations, with the effect less evident in people with mild anxiety symptoms. No adverse effects, including memory loss or collapse of psychometric functions, were observed.

CONCLUSION: may be helpful in treating some symptoms in neuropsychiatric patients.

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