Abstract Title:

Passiflora alata and Passiflora edulis spray-dried aqueous extracts inhibit inflammation in mouse model of pleurisy.

Abstract Source:

Fitoterapia. 2007 Feb;78(2):112-9. Epub 2006 Nov 14. PMID: 17215089

Abstract Author(s):

A J Vargas, D S Geremias, G Provensi, P E Fornari, F H Reginatto, G Gosmann, E P Schenkel, T S Fröde

Abstract:

The aqueous leaves extracts of Passiflora alata (100-300 mg/kg, i.p.) and Passiflora edulis (100-1000 mg/kg, i.p.) possess a significant antiinflammatory activity on carrageenan-induced pleurisy in mice. Treatment with the extracts inhibited leukocyte migration and reduced the formation of exudate. Moreover, a significant inhibition of myeloperoxidase and adenosine-deaminase activities was observed at the doses tested (100 or 250 mg/kg, i.p.). At the same doses, a significant decrease of serum C-reactive protein was observed.

Study Type : Animal Study
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