Pediatric Wells syndrome (eosinophilic cellulitis) after vaccination. - GreenMedInfo Summary
Pediatric Wells syndrome (eosinophilic cellulitis) after vaccination: A case report and review of the literature.
Pediatr Dermatol. 2018 Sep ;35(5):e262-e264. Epub 2018 Jul 12. PMID: 29998475
Ashley M Yu
A 4-year-old boy presented with erythematous vesicular plaques, ulceration, edema, and pruritus on the left foot and ankle 10 days after receiving the tetanus, diphtheria, pertussis, and polio; measles, mumps, rubella, and varicella; and hepatitis A/B vaccines. Biopsy showed eosinophilic infiltrates and flame figures, suggesting Wells syndrome. Patch testing showed a 1+ reaction to neomycin and aluminum hydroxide, with arecall reaction of Wells syndrome of the feet bilaterally. We report a rare case of pediatric Wells syndrome triggered by nonthimerosal vaccine components confirmed by patch testing.