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Abstract Title:

Efficacy and possible mechanisms of perillaldehyde in control of Aspergillus niger causing grape decay.

Abstract Source:

Int J Food Microbiol. 2015 Jun 2 ;202:27-34. Epub 2015 Feb 27. PMID: 25755082

Abstract Author(s):

Jun Tian, Yanzhen Wang, Hong Zeng, Zongyun Li, Peng Zhang, Akalate Tessema, Xue Peng

Article Affiliation:

Jun Tian

Abstract:

A variety of plant products have been recognized for their antifungal activity and recently have attracted food industry attention for their efficacy in controlling postharvest fungal decay of fruits. The antifungal activity of perillaldehyde (PAE) was evaluated against Aspergillus niger, a known cause of grape spoilage, and possible mechanisms were explored. PAE showed notable antifungal activity against A. niger, with a minimum inhibitory concentration (MIC) and a minimum fungicidal concentration (MFC) of 0.25 and 1μl/ml, respectively. The accumulation of mycelial biomass was also inhibited by PAE in a dose-dependent manner, completely inhibiting mycelial growth at 1 μl/ml. In vivo data confirmed that the vapour treatment of grapes with various concentrations of PAE markedly improved control of A. niger andsuppressed natural decay. Concentrations of PAE of 0.075 μl/ml air showed the greatest inhibition of fungal growth compared to the controls. Further experiments indicated that PAE activated a membrane-active mechanism that inhibits ergosterol synthesis, increases membrane permeability (as evidencedby extracellular pH and conductivity measurements), and disrupts membrane integrity, leading to cell death. Our findings suggest that this membrane-active mechanism makes PAE a promising potential antifungal agent for postharvest control of grape spoilage.

Study Type : Plant Study

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