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Abstract Title:

Perspectives on the Combined Effects ofandExtracts in Terms of Phytochemical Profile and Pharmacological Effects.

Abstract Source:

Plants (Basel). 2021 Jul 7 ;10(7). Epub 2021 Jul 7. PMID: 34371593

Abstract Author(s):

Andreea-Ina Antonescu Mintas, Florina Miere Groza, Luminita Fritea, Mariana Ganea, Mihaela Zdrinca, Luciana Dobjanschi, Angela Antonescu, Simona Ioana Vicas, Florin Bodog, Rakesh K Sindhu, Simona Cavalu

Article Affiliation:

Andreea-Ina Antonescu Mintas

Abstract:

Nowadays, the tendency in pharmaceutical and food industries is to replace synthetic antioxidants with the natural ones. For this reason, there is a growing interest in analyzing natural, healthy and non-toxic additives as potential antioxidants. Some plants, which contain high levels of phenolic compounds, present an increasing interest for medicine due to their ability to scavenge free radicals, along with other pharmacological activities, such as antibacterial activity, wound healing and anti-inflammatory effect, to mention only a few. The aim of this review is to explore the therapeutic potential ofandin relation with their phytochemical profile and to highlight the pharmacological activity of aqueous or ethanol extracts. Special attention was devoted to the dermal pathology and wound healing effects, in the context of multiple skin conditions such as acne, eczema boils, psoriasis and rashes. Additionally, both extracts (sp. andsp.) are characterized by high content of antioxidant compounds, which are responsible for the radiance and resistance of the skin and slowing down of the aging process by maintaining estrogen levels. Moreover, the potential combined effect of the mixed extract is pointed out in terms of future applications for wound healing, based on some preliminary results obtained from a "scratch tests" assay performed with respect to human dermal fibroblasts.

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