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Article Publish Status: FREE
Abstract Title:

Pharmacological Activity of Eriodictyol: The Major Natural Polyphenolic Flavanone.

Abstract Source:

Evid Based Complement Alternat Med. 2020 ;2020:6681352. Epub 2020 Dec 12. PMID: 33414838

Abstract Author(s):

Zirong Deng, Sabba Hassan, Muhammad Rafiq, Hongshui Li, Yang He, Yi Cai, Xi Kang, Zhaoguo Liu, Tingdong Yan

Article Affiliation:

Zirong Deng

Abstract:

Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is an effective natural drug source to maintain higher health standards due to its excellent therapeutic roles in neuroprotection, cardioprotective activity, hepatoprotective activity, antidiabetes and obesity, and skin protection and having highly analgesic, antioxidant, and anti-inflammatory effects, antipyretic and antinociceptive actions, antitumor activity, and much more. This review aims to highlight the modes of action of eriodictyol against various diseases via multiple cellular signaling pathways.

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