Abstract Title:

Effect of plant extracts on trans-sialidase activity in human blood plasma.

Abstract Source:

Bull Exp Biol Med. 2007 Jan;143(1):46-50. PMID: 18019010

Abstract Author(s):

D V Aksenov, V V Kaplun, V V Tertov, I A Sobenin, A N Orekhov

Abstract:

We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum inhibitory effect. trans-Sialidase activity of blood plasma ex vivo decreased 2-fold after peroral administration of pollen and garlic powder. A correlation was found between the decrease in trans-sialidase activity in blood plasma and ability of blood plasma to induce cholesterol accumulation in cultured cells from the intact human aortic intima.

Study Type : In Vitro Study

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