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Abstract Title:

The Antioxidative, Antiaging, and Hepatoprotective Effects of Alkali-Extractable Polysaccharides by.

Abstract Source:

Evid Based Complement Alternat Med. 2017 ;2017:7298683. Epub 2017 Aug 22. PMID: 29104605

Abstract Author(s):

Shangshang Li, Juan Li, Jianjun Zhang, Wenshuai Wang, Xiuxiu Wang, Huijuan Jing, Zhenzhen Ren, Zheng Gao, Xinling Song, Zhiyuan Gong, Le Jia

Article Affiliation:

Shangshang Li

Abstract:

The aim of this work was designed to investigate the antioxidant, antiaging, and hepatoprotective effects of alkali-extractable polysaccharides (AlAPS) and their three purified fractions (AlAPS-1, AlAPS-2, and AlAPS-3) fromin D-galactose induced aging mice. Forantioxidant analysis, both AlAPS and its fractions exhibited moderate reducing power, Fe-chelating activities, and potent scavenging activities on hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Theresults demonstrated that the polysaccharides, especially AlAPS-2, showed potential antiaging and hepatoprotective effects by enhancing the antioxidant status, decreasing serum hepatic enzyme activities, and improving the lipid metabolism. This study suggested that the polysaccharides extracted and purified fromcould be exploited as a potent dietary supplement to attenuate aging and prevent age-related diseases.

Study Type : In Vitro Study

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Sayer Ji
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