n/a
Abstract Title:

Polysaccharides from Cordyceps miltaris cultured at different pH: Sugar composition and antioxidant activity.

Abstract Source:

Int J Biol Macromol. 2020 Jun 20 ;162:349-358. Epub 2020 Jun 20. PMID: 32574745

Abstract Author(s):

Yuntao Liu, Yiwen Li, Huilan Zhang, Cheng Li, Zhiqing Zhang, Aiping Liu, Hong Chen, Bin Hu, Qingying Luo, Bokun Lin, Wenjuan Wu

Article Affiliation:

Yuntao Liu

Abstract:

In the study, theβ-glucan content, the primary structure and the antioxidant capacity of polysaccharides in Cordyceps militaris cultivated with different initial growth pH were evaluated. Meanwhile, the mechanism of β-glucan biosynthesis was investigated by RNA-Seq. Based on the results, C. militaris growing at aninitial growth pH of 5-7 (CMsA) was distinguished from C. militaris growing at an initial growth pH of 8-9 (CMsB) and their unigenes showed the comparable expression. The mean of β-glucan content of CMsB group was 32.7% (w/w), 10% higher than that of CMsA. The results of RNA-seq showed 1088 differentially expressed genes between CMsA and CMsB groups. Furthermore, oxidative phosphorylation-related Gene ontology terms were up-regulated in CMsB groups. In addition, the results of structural analysis (FTIR spectrum, monosaccharide composition, periodate oxidation) and bioactivity evaluation speculated that C. militaris polysaccharides possessed higher β-(1 → 6)-glucan content and antioxidant activities in CMsB groups.

Study Type : In Vitro Study

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.