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Abstract Title:

Protective role of allicin and L-ascorbic acid against the genotoxic damage induced by chlormadinone acetate in cultured human lymphocytes.

Abstract Source:

Indian J Exp Biol. 2005 Sep ;43(9):769-72. PMID: 16187526

Abstract Author(s):

Yasir Hasan Siddique, Mohammad Afzal

Article Affiliation:

Yasir Hasan Siddique

Abstract:

In our present study, different doses of allicin and L-ascorbic acid were tested against the genotoxic damage induced by chlormadinone acetate (CMA; 40 microM) using chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) as the parameters. Treatment with allicin and L-ascorbic acid resulted in reduction of CAs and SCEs. The results suggested a protective role of allicin and L-ascorbic acid against CMA induced genotoxic damage.

Study Type : Human In Vitro

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