Abstract Title:

Behçet syndrome: effects of Pycnogenol® supplementation during regression phases.

Abstract Source:

Minerva Cardioangiol. 2018 Aug ;66(4):386-390. PMID: 29975020

Abstract Author(s):

Shu Hu, Gianni Belcaro, Andrea Ledda, Marcello Corsi, Roberto Cotellese, Beatrice Feragalli, Morio Hosoi, Mark Dugall, Patrizia Torino-Rodriguez, Maria R Cesarone

Article Affiliation:

Shu Hu


BACKGROUND: The aim of this comparative registry study was to evaluate the supplementation with Pycnogenol® in subjects with Behçet syndrome (BS) with symptoms impairing their quality of life despite being in a remitting phase of the disease.

METHODS: Thirty-four patients with a confirmed diagnosis of BS were divided into the control group (without supplement) or the active group, in this specific case using Pycnogenol® (Horphag Research LTD) supplement at the daily dose of 150 mg (50 mg tid) for 4 weeks.

RESULTS: All subjects receiving Pycnogenol® reported a significant decrease in symptoms, such as burning/pain due to dryness and ulcerations (P<0.05). In addition, Pycnogenol® showed important anti-inflammatory activity by decreasing ESR, leucocytosis and Pathergy Test response.

CONCLUSIONS: Pycnogenol® may be a useful supplementation for the management of BS.

Study Type : Human Study

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Sayer Ji
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