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Abstract Title:

Biomonitoring of estrogen and melatonin metabolites among women residing near radio and television broadcasting transmitters.

Abstract Source:

J Occup Environ Med. 2007 Oct ;49(10):1149-56. PMID: 18000420

Abstract Author(s):

Maggie L Clark, James B Burch, Michael G Yost, Yusheng Zhai, Annette M Bachand, Cole T E Fitzpatrick, Jaya Ramaprasad, Lori A Cragin, John S Reif

Article Affiliation:

Maggie L Clark

Abstract:

OBJECTIVES: Metabolites of estrogen (estrone-3-glucuronide [E1G]) and melatonin (6-hydroxymelatonin sulfate [6-OHMS]) were characterized among women living in a community with increased radiofrequency (RF) exposure from radio and television transmitters.

METHODS: RF spot measurements, and personal 60-Hz magnetic field and residential parameters were collected. Overnight urine samples were assayed for E1G and 6-OHMS excretion.

RESULTS: Among premenopausal women, there were no associations between RF or 60-Hz nonionizing radiation and E1G or 6-OHMS excretion. Among postmenopausal women, increased residential RF exposures, transmitter proximity and visibility, and temporally stable 60-Hz exposures were significantly associated with increased E1G excretion. This association was strongest among postmenopausal women with low overnight 6-OHMS levels.

CONCLUSIONS: RF and temporally stable 60-Hz exposures were associated with increased E1G excretion among postmenopausal women. Women with reduced nocturnal 6-OHMS excretion may represent a sensitive subgroup.

Study Type : Human Study

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