n/a
Abstract Title:

[An association of selected polymorphisms of the lactoferrin gene and genes for lactoferrin receptors in the prevalence of metabolic disorders in obese subjects].

Abstract Source:

Pol Merkur Lekarski. 2020 Apr 22 ;48(284):120-123. PMID: 32352945

Abstract Author(s):

Nina Kaczmarek, Małgorzata Jamka, Jarosław Walkowiak

Article Affiliation:

Nina Kaczmarek

Abstract:

Lactoferrin is a multipotent protein that belongs to the transferrin family. It was first isolated from cow's milk in 1939. In the 1960s, it was also found in breast milk. In the human body, lactoferrin can also be found in other body fluids, e.g., saliva, tears, and vaginal discharge. Its biological activity depends on receptors present on the membrane surface of many cells, such as neutrophils, hepatocytes, and intestinal epithelial cells. Lactoferrin can bind iron. Because of this property, it also has antibacterial, antiviral, and antifungal activity. Its antiinflammatory and anticancer activity has also been confirmed. Recent studies have demonstrated that lactoferrin might have a beneficial effect in the prevention and treatment of obesity-related metabolic abnormalities, such as type 2 diabetes, hypertension, and dyslipidaemia. It is also worth to notice the potential relationship between polymorphisms in lactoferrin gene, genes for lactoferrin receptors and metabolic abnormalities in obese subjects.

Print Options


Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.