Abstract Title:

Redox regulation of plant stem cell fate.

Abstract Source:

EMBO J. 2017 10 2 ;36(19):2844-2855. Epub 2017 Aug 24. PMID: 28838936

Abstract Author(s):

Jian Zeng, Zhicheng Dong, Haijun Wu, Zhaoxia Tian, Zhong Zhao

Article Affiliation:

Jian Zeng


Despite the importance of stem cells in plant and animal development, the common mechanisms of stem cell maintenance in both systems have remained elusive. Recently, the importance of hydrogen peroxide (HO) signaling in priming stem cell differentiation has been extensively studied in animals. Here, we show that different forms of reactive oxygen species (ROS) have antagonistic roles in plant stem cell regulation, which were established by distinct spatiotemporal patterns of ROS-metabolizing enzymes. The superoxide anion (O2·-) is markedly enriched in stem cells to activateand maintain stemness, whereas HOis more abundant in the differentiating peripheral zone to promote stem cell differentiation. Moreover, HOnegatively regulates O2·- biosynthesis in stem cells, and increasing HOlevels or scavenging O2·- leads to the termination of stem cells. Our results provide a mechanistic framework for ROS-mediated control of plant stem cell fate and demonstrate that the balance between O2·- and HOis key to stem cell maintenance and differentiation.

Study Type : Plant Study
Additional Links
Additional Keywords : Plant Stem Cells

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.