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Article Publish Status: FREE
Abstract Title:

Maintenance Therapy Containing Metformin and/or Zyflamend for Advanced Prostate Cancer: A Case Series.

Abstract Source:

Case Rep Oncol Med. 2015 ;2015:471861. Epub 2015 Mar 15. PMID: 25861496

Abstract Author(s):

Mehmet Asim Bilen, Sue-Hwa Lin, Dean G Tang, Kinjal Parikh, Mong-Hong Lee, Sai-Ching J Yeung, Shi-Ming Tu

Article Affiliation:

Mehmet Asim Bilen

Abstract:

Metformin is derived from galegine, a natural ingredient, and recent studies have suggested that metformin could enhance the antitumor effects of hormone ablative therapy or chemotherapy and reduce prostate cancer-specific mortality. Zyflamend is a combination of herbal extracts that reduces inflammation and comprises turmeric, holy basil, green tea, oregano, ginger, rosemary, Chinese goldthread, hu zhang, barberry, and basil skullcap. We propose a maintenance regimen with metformin and/or Zyflamend that targets cancer stem cells and the tumor microenvironment to keep the cancer dormant and prevent it from activation from dormancy. Herein, we report the clinical course of four patients who experienced a clinical response after treatment with metformin and/or Zyflamend.

Study Type : Human Study

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Sayer Ji
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