Abstract Title:

Resveratrol activity on guinea pig isolated trachea from normal and albumin-sensitized animals.

Abstract Source:

Pharmacol Res Commun. 1988 Dec;20 Suppl 5:79-82. PMID: 2907791

Abstract Author(s):

E Ragazzi, G Froldi, G Fassina

Article Affiliation:

Department of Pharmacology, University of Padua, Padova, Italy.


The relaxant effect of resveratrol on guinea pig isolated trachea (EC50 = 100 microM) was not due to interactions with histaminergic or cholinergic systems, but appeared to be influenced by beta-blockers, indomethacin and mepacrine. Antigen-induced contraction on sensitized trachea was partially antagonized by resveratrol. Resveratrol action may be partially related to arachidonic acid metabolism.

Study Type : Animal Study

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