Resveratrol antagonizes antigen-induced contractions in the guinea pig trachea. - GreenMedInfo Summary
Resveratrol activity on guinea pig isolated trachea from normal and albumin-sensitized animals.
Pharmacol Res Commun. 1988 Dec;20 Suppl 5:79-82. PMID: 2907791
Department of Pharmacology, University of Padua, Padova, Italy.
The relaxant effect of resveratrol on guinea pig isolated trachea (EC50 = 100 microM) was not due to interactions with histaminergic or cholinergic systems, but appeared to be influenced by beta-blockers, indomethacin and mepacrine. Antigen-induced contraction on sensitized trachea was partially antagonized by resveratrol. Resveratrol action may be partially related to arachidonic acid metabolism.