Resveratrol, vitamin C and/or vitamin E are effective in protecting cells against oxidative damage. - GreenMedInfo Summary
Abstract Title:
Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells.
Abstract Source:
Neuroreport. 1997 Apr 14;8(6):1499-502. PMID: 9172162
Article Affiliation:
Department of Pharmacology, University of Missouri, Columbia 65212, USA.
Abstract:
The goal of this study was to investigate the effect of resveratrol, an active ingredient found in grapes and other plant products, in ameliorating oxidative stress. Oxidative stress was induced by addition of Fe2+ and t-butyl hydroperoxide to the cultured PC12 cell medium. Resveratrol, vitamins C and/or E, were added to the cell culture medium during oxidative stress. The combination of resveratrol and vitamins C and/or E was more effective in protecting the cell than was any of these three antioxidants alone.
Article Published Date : Apr 14, 1997
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(1649) : AC(947), Stilbenes : CK(153) : AC(106), Vitamin C : CK(3397) : AC(792), Vitamin E : CK(2077) : AC(371)
Pharmacological Actions : Antioxidants : CK(14410) : AC(5758)