This review collates the current scientific understanding on the mechanism of anti-cancer activity of honey. - GreenMedInfo Summary

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Abstract Title:

Honey and cancer: A mechanistic review.

Abstract Source:

Clin Nutr. 2018 Dec 27. Epub 2018 Dec 27. PMID: 30639116

Abstract Author(s):

Marwa Waheed, Muhammad Bilal Hussain, Ahsan Javed, Zarina Mushtaq, Sadia Hassan, Mohammad Ali Shariati, Muhammad Usman Khan, Majid Majeed, Manisha Nigam, Abhay Prakash Mishra, Mojtaba Heydari

Article Affiliation:

Marwa Waheed

Abstract:

BACKGROUND: Globally, cancer ranks among the most common causes of death. Multiple experimental and clinical studies have investigated anticancer effects of honey with promising results. This study focused on potential background mechanisms of this effect.

METHODS: The current literature was reviewed for potential anticancer pathways which are suggested for honey and its ingredients.

RESULTS: Flavonoids (kaempferol, catechin, and quercetin) and phenolic acids (caffeic acid and gallic acid) are the most important ingredients of honey with known anti-cancer activity. The main suggested mechanisms for anti-cancer activity of honey and its ingredients are antioxidant, apoptotic, tumor necrosis factor inhibiting, antiproliferative, immunomodulatory, anti-inflammatory and estrogenic effects.

CONCLUSION: This review collates the current scientific understanding on the mechanism of anti-cancer activity of honey.

Article Published Date : Dec 26, 2018
Study Type : Review
Additional Links
Substances : Honey : CK(920) : AC(305)
Diseases : Cancers: All : CK(28241) : AC(13477)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(13987), Antioxidants : CK(21528) : AC(13231), Antiproliferative : CK(6801) : AC(6958), Apoptotic : CK(6986) : AC(6931), Immunomodulatory : CK(4048) : AC(2154), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(4342)

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Key Research Topics

Disease

Cancers: All

Pharmacological Actions

Anti-Inflammatory Agents
Antioxidants
Immunomodulatory
Apoptotic
Antiproliferative
Tumor Necrosis Factor (TNF) Alpha Inhibitor

Substance

Honey

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