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Article Publish Status: FREE
Abstract Title:

Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review.

Abstract Source:

J Trop Med. 2016 ;2016:2853045. Epub 2016 Nov 13. PMID: 27956904

Abstract Author(s):

Sin-Yeang Teow, Kitson Liew, Syed A Ali, Alan Soo-Beng Khoo, Suat-Cheng Peh

Article Affiliation:

Sin-Yeang Teow

Abstract:

Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against Staphylococcus aureus (S. aureus). As demonstrated by in vitro experiment, curcumin exerts even more potent effects when used in combination with various other antibacterial agents. Hence, curcumin which is a natural product derived from plant is believed to have profound medicinal benefits and could be potentially developed into a naturally derived antibiotic in the future. However, there are several noteworthy challenges in the development of curcumin as a medicine. S. aureus infections, particularly those caused by the multidrug-resistant strains, have emerged as a global health issue and urgent action is needed. This review focuses on the antibacterial activities of curcumin against both methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). We also attempt to highlight the potential challenges in the effort of developing curcumin into a therapeutic antibacterial agent.

Study Type : Review

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