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Abstract Title:

Antiviral Activities of Silymarin and Derivatives.

Abstract Source:

Molecules. 2019 Apr 19 ;24(8). Epub 2019 Apr 19. PMID: 31010179

Abstract Author(s):

Ching-Hsuan Liu, Alagie Jassey, Hsin-Ya Hsu, Liang-Tzung Lin

Article Affiliation:

Ching-Hsuan Liu

Abstract:

Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective functions. Recent studies have also documented the antiviral activities of silymarin and its derivatives against several viruses, including the flaviviruses (hepatitis C virus and dengue virus), togaviruses (Chikungunya virus and Mayaro virus), influenza virus, human immunodeficiency virus, and hepatitis B virus. This review will describe some of the latest preclinical and clinical studies detailing the antiviral profiles of silymarin and its derivatives, and discuss their relevance for antiviral drug development.

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Sayer Ji
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