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Abstract Title:

Curcumin and endometriosis: Review on potential roles and molecular mechanisms.

Abstract Source:

Biomed Pharmacother. 2017 Oct 25 ;97:91-97. Epub 2017 Oct 25. PMID: 29080464

Abstract Author(s):

Tahereh Arablou, Roya Kolahdouz-Mohammadi

Article Affiliation:

Tahereh Arablou

Abstract:

Endometriosis, an estrogen-dependent inflammatory disease, is one of the most common chronic gynecological disorders affecting women in reproductive age. It is characterized by the presence of endometrial-like tissue outside the uterus. The exact pathophysiology of endometriosis is not still well-known, but the immune system and inflammation have been considered as pivotal factors in disease progression. Turmeric, an important spice all around the world, is obtained from the rhizomes of Curcuma longa, a member of the Zingiberaceae family. It has been used in the prevention and treatment of many diseases since ancient times. Curcumin is the principal polyphenol isolated from turmeric. Several evidences have shown the anti-inflammatory, antioxidant, anti-tumor, anti-angiogenesis, and anti-metastatic activities of curcumin. In this review, relevant articles on the effect of curcumin on endometriosis and possible molecular mechanisms are discussed.

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Sayer Ji
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