Sea cucumber contains antifungal compounds. - GreenMedInfo Summary
Antifungal triterpene glycosides from the sea cucumber Bohadschia marmorata.
Planta Med. 2008 Dec 18. PMID: 19096993
Four new holostan-type triterpene glycosides, marmoratoside A ( 1), 17 alpha-hydroxy impatienside A ( 2), marmoratoside B ( 3), 25-acetoxy bivittoside D ( 4), together with two known triterpene glycosides, impatienside A ( 5) and bivittoside D ( 6), were isolated from the sea cucumber BOHADSCHIA MARMORATA Jaeger. On the basis of spectroscopic analyses, including two-dimensional NMR techniques, and chemical reactions, the structures of the new triterpene glycosides were elucidated. Compounds 1, 2, 5, and 6 exhibited significant antifungal activity against six strains (0.70 </= MIC (80) </= 2.81 muM).