Sedentary behavior has a strong association with cardiovascular disease risk. - GreenMedInfo Summary
Sedentary Behavior and Cardiovascular Disease Risk: Mediating Mechanisms.
Exerc Sport Sci Rev. 2017 Apr ;45(2):80-86. PMID: 28118158
Sedentary behavior has a strong association with cardiovascular disease (CVD) risk, which may be independent of physical activity. To date, the mechanism(s) that mediate this relationship are poorly understood. We hypothesize that sedentary behavior modifies key hemodynamic, inflammatory, and metabolic processes resulting in impaired arterial health. Subsequently, these vascular impairments directly and indirectly contribute to the development of CVD.