From seeds of Apium graveolens Linn. to a cerebral ischemia medicine: The long Journey of 3-n-Butylphthalide. - GreenMedInfo Summary
From Seeds of Apium graveolens Linn. to a Cerebral Ischemia Medicine: The Long Journey of 3-n-Butylphthalide.
J Med Chem. 2020 Jul 16. Epub 2020 Jul 16. PMID: 32672958
José Marco-Contelles
3-n-Butylphthalide (NBP) as well as its derivatives and analogues (NBPs), in racemic or enantiomerically pure forms, possess potent and diverse pharmacological properties, and have shown a great potential therapeutic interest for many human conditions, especially for cerebral ischemia. This Perspective outlines the synthesis and therapeutic applications of NBPs.