Abstract Title:

Serum vitamin D level is negatively associated with carotid atherosclerosis in Korean adults.

Abstract Source:

Int J Food Sci Nutr. 2016 Aug 18:1-7. Epub 2016 Aug 18. PMID: 27537342

Abstract Author(s):

Yeon-Kyeong Choi, Sang-Wook Song, Bo-Ra Shin, Jeong-Ah Kim, Ha-Na Kim

Article Affiliation:

Yeon-Kyeong Choi

Abstract:

The present study investigated the associations between serum vitamin D levels and carotid intima-media thickness (CIMT), carotid plaque and atherosclerosis in 71 Korean adults. CIMT and the presence of carotid plaque were assessed with a high-resolution B-mode ultrasound system, and carotid atherosclerosis was defined as a mean CIMT value>0.9 mm or the presence of carotid plaque. A vitamin D deficiency was associated with the presence of carotid plaque (adjusted odds ratio [aOR]: 9.25, 95% confidence interval [CI]: 1.52-56.3; p = 0.016). As serum vitamin D levels increased, the presence of high-risk carotid plaque decreased (aOR:0.84, 95%CI: 0.72-0.99; p = 0.039). Serum vitamin D levels was negatively associated with carotid atherosclerosis (aOR: 0.86, 95%CI: 0.76-0.97; p = 0.018). Further studies are needed to investigate whether vitamin D supplementation would be effective for the prevention of atherosclerosis andcardiovascular diseases.

Study Type : Human Study

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