n/a
Article Publish Status: FREE
Abstract Title:

Immunomodulatory and Inhibitory Effect of Immulina, and Immunlogesin the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in Allergic Inflammatory Responses.

Abstract Source:

Plants (Basel). 2018 Feb 26 ;7(1). Epub 2018 Feb 26. PMID: 29495393

Abstract Author(s):

Kurt Appel, Eduardo Munoz, Carmen Navarrete, Cristina Cruz-Teno, Andreas Biller, Eva Thiemann

Article Affiliation:

Kurt Appel

Abstract:

Immulina, a high-molecular-weight polysaccharide extract from the cyanobacterium() is a potent activator of innate immune cells. On the other hand, it is well documented thatexerts anti-inflammatory effects and showed promising effects with respect to the relief of allergic rhinitis symptoms. Taking into account these findings, we decided to elucidate whether Immulina, and immunLoges(a commercial available multicomponent nutraceutical with Immulinaas a main ingredient) beyond immune-enhancing effects, might also exert inhibitory effects in the induced allergic inflammatory response and on histamine release from RBL-2H3 mast cells. Our findings show that Immulinaand immunLogesinhibited the IgE-antigen complex-induced production of TNF-α, IL-4, leukotrienes and histamine. The compound 48/80 stimulated histamine release in RBL-2H3 cells was also inhibited. Taken together, our results showed that Immulinaand immunLogesexhibit anti-inflammatory properties and inhibited the release of histamine from mast cells.

Study Type : In Vitro Study

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.