Spontaneous regression of breast cancer after biopsy. - GreenMedInfo Summary
[Spontaneous regression of breast cancer after biopsy. About two cases].
Gynecol Obstet Fertil. 2014 Apr ;42(4):269-72. Epub 2014 Jan 3. PMID: 24394327
We report two cases of spontaneous regression of breast cancer occurred in our institution. It was about a 34- and an 82-year-old patient. The examination revealed a palpable nodule. In both cases, biopsy revealed a negative immunohistochemical staining for estrogen and progesterone receptors, and HER-2 negative. Histological analysis of the surgical specimen found fibrous tissue rearrangement without carcinoma. In the first case, a sarcoidosis was diagnosed at the same time, the mediastinal nodes mimicked a metastatic cancer. These cases illustrate a rare phenomenon. The main hypothesis is a carcinoma- directed immune response triggered by the biopsy.