Spontaneous remission of a squamous cell carcinoma of the floor of the mouth. - GreenMedInfo Summary
Spontaneous remission of a squamous cell carcinoma of the floor of the mouth.
J Craniomaxillofac Surg. 2014 Oct ;42(7):1536-9. Epub 2014 May 9. PMID: 24958155
Alexandre de Andrade Sousa
Spontaneous remission is a rare, but well recognized event in oncology. Certain tumours, such as melanomas, hypernephromas and neuroblastomas, are known for showing spontaneous regression. Similarly, spontaneous regression of oral lymphomas, as well as oropharyngeal and recurrent tongue carcinomas, has been reported. Here, we present a novel case of a patient with a primary squamous cell carcinoma on the floor of the mouth whose tumour regressed spontaneously in three months, without any treatment. We also review of the literature on the spontaneous remission of oral cancer and discuss possible mechanisms for this phenomenon.