Abstract Title:

[Squamous cell carcinoma in ulcer after bacille Calmette-Guérin vaccination].

Abstract Source:

Ugeskr Laeger. 2014 Oct 13 ;176(42). PMID: 25316362

Abstract Author(s):

Rikke Maria Nielsen, Flemming Andersen, Maria Luise Salskov-Iversen

Article Affiliation:

Rikke Maria Nielsen


Marjolin's ulcer is an aggressive squamous cell carcinoma (SCC) found in chronically inflamed skin. SCC has been reported in smallpox vaccination sites, whereas basal cell carcinomas are more common in scar after bacille Calmette-Guérin (BCG) vaccination. A 72-year-old man presented with a chronic ulcer at the site of his childhood BCG vaccination. At the time of examination, a 3 × 1.5 cm fleshy and secreting ulcer was found on the shoulder. Biopsy revealed SCC, and the tumour was surgically removed. In conclusion, chronic ulcers, especially those originating in chronically inflamed skin, should be regularly biopsied to assure that malignant transformation has not occurred.

Study Type : Human: Case Report

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