Abstract Title:

Simvastatin-associated memory loss.

Abstract Source:

Pharmacotherapy. 2001 Jun ;21(6):767-9. PMID: 11401190

Abstract Author(s):

A Orsi, O Sherman, Z Woldeselassie

Article Affiliation:

Pharmacy Program, Bronx VA Medical Center, New York 10468, USA.


The statins are widely used to treat dyslipidemias. They are generally associated with mild adverse effects, but rarely, more serious reactions may occur. A 51-year-old man experienced delayed-onset, progressive memory loss while receiving simvastatin for hypercholesterolemia. His therapy was switched to pravastatin, and memory loss resolved gradually over the next month, with no recurrence of the adverse effect.

Study Type : Human: Case Report
Additional Links
Adverse Pharmacological Actions : Neurotoxic : CK(1458) : AC(323)

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