Sulforaphane's antioxidant, anti-inflammatory, and histone deacetylase inhibiting properties may improve schizophrenia symptoms. - GreenMedInfo Summary

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Abstract Title:

[Role of sulforaphane in improving negative symptoms and cognitive symptoms of schizophrenia and the underlying mechanism].

Abstract Source:

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Jun 28 ;44(6):701-705. PMID: 31304933

Abstract Author(s):

Ye Yang, Ranran Li, Gangrui Hei, Renrong Wu

Article Affiliation:

Ye Yang

Abstract:

The negative symptoms and cognitive symptoms of schizophrenia patients are still clinical problems to be solved. Schizophrenia patients are abnormal in oxidative stress, immune regulation, and anti-histone deacetylase (HDAC), while sulforaphane plays a role in anti-oxidative stress, anti-inflammation, and anti-HDAC. Therefore, the sulforaphane could improve the negative symptoms and cognitive deficits of schizophrenia.

Article Published Date : Jun 28, 2019

Study Type : Review

Additional Links

Substances : Sulforaphane : CK(930) : AC(611)

Diseases : Schizophrenia : CK(861) : AC(180), Schizophrenic Disorders : CK(26) : AC(6)

Pharmacological Actions : Anti Inflammatory, Antioxidant Effects : CK(157) : AC(44), Histone deacetylase inhibitor : CK(98) : AC(76)

Additional Keywords : Isothiocyanates : CK(240) : AC(100)