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Article Publish Status: FREE
Abstract Title:

The effect of 'Zesy002' kiwifruit (var.) on gut health function: a randomised cross-over clinical trial.

Abstract Source:

J Nutr Sci. 2019 ;8:e18. Epub 2019 May 3. PMID: 31080591

Abstract Author(s):

Sarah L Eady, Alison J Wallace, Christine A Butts, Duncan Hedderley, Lynley Drummond, Juliet Ansell, Richard B Gearry

Article Affiliation:

Sarah L Eady

Abstract:

Functional gastrointestinal disorders including constipation affect up to 14 % of the world's population. Treatment is difficult and challenging resulting in a need for alternative safe and effective therapies. The present study investigated whether daily consumption of three gold-fleshed kiwifruit could alleviate constipation and improve gastrointestinal discomfort in mildly constipated individuals with and without pain. A total of thirty-two participants were enrolled in a 16-week randomised, single-blind, crossover study. Participants received either three 'Zesy002' kiwifruit or 14·75 g Metamucil(5 g dietary fibre/d (a positive control)) for 4 weeks each with a 4-week washout between treatments. A 2-week washout period was included at the beginning and end of the study. Daily bowel habit diaries were kept throughout the study. The primary outcome measure was differences in the number of complete spontaneous bowel movements (CSBM). Secondary outcome measures were bowel movement frequency and stool form as well as digestive symptoms and comfort. The number of CSBM per week was significantly greater during daily consumption of three kiwifruit compared with the baseline (6·33·3;<0·05) and the Metamuciltreatment (6·34·5;<0·05). Stool consistency was also improved, with kiwifruit producing softer stools and less straining (<0·05). Gastrointestinal discomfort was also improved compared with baseline for abdominal pain, constipation and indigestion (<0·05) during the kiwifruit intervention and constipation during the Metamucilintervention (<0·05). This randomised controlled trial demonstrates that daily consumption of three gold-fleshed kiwifruit is associated with a significant increase of two CSBM per week and reduction in gastrointestinal discomfort in mildly constipated adults.

Study Type : Human Study

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