Abstract Title:

Citrus limetta leaves extract antagonizes the hypertensive effect of angiotensin II.

Abstract Source:

J Ethnopharmacol. 2010 Feb 8. Epub 2010 Feb 8. PMID: 20149855

Abstract Author(s):

Yolanda Y Perez, Enrique Jimenez-Ferrer, Daniel Alonso, Carol A Botello-Amaro, Alejandro Zamilpa

Article Affiliation:

Centro de Investigacion Biomedica del Sur, Instituto Mexicano del Seguro Social, Argentina 1, Centro, 62790, Xochitepec, Morelos, Mexico.


Ethnopharmacological relevance: Citrus limetta Risso (Rutaceae) is widely used in Mexico for healing purposes, among them as antihypertensive treatment.Aim of the study:To assess the antihypertensive effect of C. limetta leaves as one of its ethnomedical uses.Materials and methods:the acute response of blood pressure to angiotensin II administration was measured in mice. Additionally, the acute oral toxicity profiles were determined. RESULTS: The findings of the current investigation showed that different concentrations of the aqueous extract prevented the raise of systolic blood pressure (p

Study Type : Animal Study

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