Abstract Title:

Childhood cancer incidence in relation to sunlight exposure.

Abstract Source:

Psychosom Med. 2004 Jul-Aug;66(4):607-13. PMID: 21102587

Abstract Author(s):

J R B Musselman, L G Spector

Article Affiliation:

Division of Pediatrics, Department of Epidemiology and Clinical Research, University of Minnesota, Minneapolis, MN 55455, USA. bruce087@umn.edu

Abstract:

BACKGROUND: There is increasing interest in the possible association between cancer incidence and vitamin D through its role as a regulator of cell growth and differentiation. Epidemiological studies in adults and one paediatric study suggest an inverse association between sunlight exposure and cancer incidence.

METHODS: We carried out an ecological study using childhood cancer registry data and two population-level surrogates of sunlight exposure, (1) latitude of the registry city or population centroid of the registry nation and (2) annual solar radiation. All models were adjusted for nation-level socioeconomic status using socioeconomic indicators.

RESULTS: Latitude and radiation were significantly associated with cancer incidence, and the direction of association was consistent between the surrogates. Findings were not consistent across tumour types.

CONCLUSION: Our ecological study offers some evidence to support an association between sunlight exposure and risk of childhood cancer.

Study Type : Meta Analysis

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