Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

n/a
Article Publish Status: FREE
Abstract Title:

A Comparative Study ofLeaves and Stems Ethanolic Extracts in terms of Antioxidant, Cytotoxic, and Antiproliferative Potential.

Abstract Source:

Evid Based Complement Alternat Med. 2018 ;2018:7860456. Epub 2018 May 16. PMID: 29887909

Abstract Author(s):

Elena-Alina Moacă, Claudia Farcaş, Alexandra Ghiţu, Dorina Coricovac, Ramona Popovici, Nela-Loredana Cărăba-Meiţă, Florina Ardelean, Diana Simona Antal, Cristina Dehelean, Ştefana Avram

Article Affiliation:

Elena-Alina Moacă

Abstract:

L. has attracted an increased interest in recent years due to its multiple pharmacological effects. This study aimed to compare twoethanolic extracts, obtained from leaves and stems, with regard to their antioxidant activity, total phenolic content, and cytotoxic effects.ethanolic extracts showed a very good antioxidant activity in the DPPH test, correlated with the content in total phenols: higher in the case offrom leaves extract (32.76 mg GAE/g) and lower forfrom stems extract (8.4 mg GAE/g). The lemon balm extracts exerted a cytotoxic effect on breast cancer cells (MDA-MB-231) even at low concentrations (100 g/mL), whereas, in the case of healthy HaCat cells,leaves extract only displayed cytotoxicity at much higher concentrations (500 and 1000 g/mL) andstems extracts were highly cytotoxic (starting at 100 g/mL). In addition, the extracts exerted inhibitory effects on cell migration and proliferation. These results provide information that confirms the high potential ofas a source of chemopreventive agents. Moreover, these data can be considered a solid background for furtherstudies involving mice bearing breast tumors.

Study Type : In Vitro Study

Print Options


Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2019 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.