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Abstract Title:

Occupational phenoxyethanol neurotoxicity: a report of three cases.

Abstract Source:

J Occup Med. 1990 Jan ;32(1):42-5. PMID: 2324842

Abstract Author(s):

W E Morton

Article Affiliation:

W E Morton

Abstract:

2-Phenoxyethanol, used as an anesthetic for handling small fish at a salmon hatchery, caused three women to experience headache and symptoms of intoxication during use, followed by diminished sensation and strength of hands and fingers, worse in the preferred hand. Persistent neuropathy did not develop in any of them. After 1 to 2 years of exposure, the women manifested gradual onset of symptoms of cognitive impairment with an inability to work. Neuropsychologic testing verified that all three had focal cognitive impairments that persisted. One also had documented labyrinthine hypofunction, which originated during this exposure. The immediate and delayed effects of 2-phenoxyethanol on the central nervous system resemble those of the other organic solvents.

Study Type : Human: Case Report
Additional Links
Anti Therapeutic Actions : Vaccination: All : CK(12698) : AC(1348)
Adverse Pharmacological Actions : Neurotoxic : CK(2424) : AC(562)

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