Three cases of toxic skin eruptions associated with methotrexate have been reported. - GreenMedInfo Summary
Three cases of toxic skin eruptions associated with methotrexate and a compilation of methotrexate-induced skin eruptions.
Dermatol Online J. 2006;12(7):15. Epub 2006 Dec 10. PMID: 17459301
Dept of Dermatology, St Lukes Roosevelt Hospital Center, New York, NY, USA. Scheinfeld@earthlink.net
Methotrexate is an antimetabolite used as a treatment for a variety of neoplastic and inflammatory diseases. It has a variety of cutaneous side effects, in particular when administered in high doses. This is a report of cutaneous eruptions in three patients treated with methotrexate and a review of eruptions linked to methotrexate.