Abstract Title:

Thymoquinone Inhibits Biofilm Formation and Attachment-Invasion in Host Cells of.

Abstract Source:

Foodborne Pathog Dis. 2019 May 9. Epub 2019 May 9. PMID: 31070474

Abstract Author(s):

Du Guo, Zeyu Yang, Xiaoying Zheng, Shenmin Kang, Zhuokai Yang, Yunfeng Xu, Chao Shi, Hongyu Tian, Xiaodong Xia

Article Affiliation:

Du Guo


is a halophilic Gram-negative foodborne pathogen that is widely distributed in marine environments. It can cause acute gastroenteritis and other diseases. This study aimed to investigate the antivirulence activity of thymoquinone (TQ) on.. TQ was shown to effectively inhibit.Subminimum inhibitory concentrations of TQ inhibited swimming and swarming motility, quorum sensing, biofilm formation, the ability ofto adhere and invade the host cells, and the expression of virulence-associated genes of.. These findings suggest that TQ can effectively inhibit the growth of.and significantly reduce its pathogenicity. Considering its safety and various biological activities, TQ has the potential to be developed as a natural antibacterial substance to reduce the diseases associated with..

Study Type : In Vitro Study

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