Abstract Title:

Topical use of Matricaria recutita L (Chamomile) Oil in the Treatment of Monosymptomatic Enuresis in Children: A Double-Blind Randomized Controlled Trial.

Abstract Source:

J Evid Based Complementary Altern Med. 2017 Jan ;22(1):12-17. Epub 2015 Sep 30. PMID: 26427789

Abstract Author(s):

Hosein Sharifi, Mohammad Bagher Minaie, Mohammad Javad Qasemzadeh, Nematollah Ataei, Mohammad Gharehbeglou, Mojtaba Heydari

Article Affiliation:

Hosein Sharifi


AIM: To evaluate the efficacy of topical use of Matricaria recutita L oil in the treatment of enuresis in children.

METHODS: Eighty patients diagnosed as monosymptomatic nocturnal or daytime enuresis were allocated to receive Matricaria recutita L (chamomile) oil or placebo topically for 6 weeks in a double-blind randomized placebo-controlled trial with a parallel design. Patients were evaluated prior to and following 8 weeks of the intervention in terms of frequency of enuresis and any observed adverse events.

RESULTS: The mean frequency of enuresis at the first, second, and third 2 weeks was lower in the intervention group compared with the placebo group, and the differences were statistically significant (P<.001, P = .03, and P<.001, respectively). There was no report of any adverse event in the study groups.

CONCLUSION: The findings of this study showed that the topical use of (chamomile) oil can decrease the frequency of nocturia in children with monosymptomatic nocturnal or daytime enuresis.

Study Type : Human Study
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