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Article Publish Status: FREE
Abstract Title:

The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb.

Abstract Source:

Clin Infect Dis. 2017 Sep 1 ;65(5):851-854. PMID: 28444156

Abstract Author(s):

Jack Bibby, Yauba Saidu, Ama Umesi, Ngozi Moneke-Anyanwoke, Adedapo O Bashorun, Mariama Badjie Hydara, Ikechukwu Adigweme, Jane U Adetifa, Michael Okoye, Elishia Roberts, Ralf Clemens, Ananda S Bandyopadhyay, Abdul K Muhammad, Sarah Mulwa, Michael Royals, Courtney Jarrahian, David Jeffries, Beate Kampmann, Ed Clarke

Article Affiliation:

Jack Bibby

Abstract:

The immunogenicity of fractional (one-fifth, 0.1 mL) intradermal doses of the inactivated poliovirus vaccine (ID fIPV) is positively correlated with the size of the intradermal fluid bleb. Training of vaccinators for campaign and routine ID fIPV administration should focus on generating an 8- to 10-mm bleb with each injection. Clinical Trials Registration NCT01847872.

Study Type : Viral

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