Two compounds from Reishi exhibit anti-aging properties in a yeast model. - GreenMedInfo Summary
Abstract Title:
Ganodermasides C and D, two new anti-aging ergosterols from spores of the medicinal mushroom Ganoderma lucidum.
Abstract Source:
Biosci Biotechnol Biochem. 2011 Apr 22. Epub 2011 Apr 22. PMID: 21512225
Article Affiliation:
College of Pharmaceutical Sciences, Zhejiang University.
Abstract:
Two new anti-aging compounds, ganodermasides C and D, were isolated and their structures elucidated. They are novel ergosterols possessing a 4,6,8(14),22-tetraene-3-one unit with unique hydroxylation at C-9. Both of them significantly extended the replicative lifespan of the K6001 yeast strain. Ganodermasides C and D regulated the expression of the gene for UTH1 to prolong the replicative lifespan of yeast.
Article Published Date : Apr 22, 2011
Study Type : In Vitro Study
Additional Links
Substances : Reishi Mushroom : CK(613) : AC(324)
Diseases : Aging : CK(5553) : AC(1332)
